Mane is in superb form for the Reds, notching 11 goals in his last 11 games for the club.
His purple patch continued away at fulham on Sunday, scoring the opening goal of the game – days after he produced a magnificent two-goal performance against Bayern Munich in the Champions League.
He also became the first Senegalese player to hit 17 goals in an English league season, surpassing Demba Ba’s record of 16 with Newcastle.
And Aldridge, who won the First Division with Liverpool in 1988, believes the former Southampton man needs two Premier League stalwarts to misfire before he can win the coveted prize.
“Every time I’ve seen Sadio Mane over the past six weeks I keep saying to him: ‘Golden Boot, Golden Boot’ because I know he’s got it in his locker to do it,” he told the Liverpool Echo.
“He’s very shy and always replies to me: “No, no, no” but all of a sudden he’s got a chance.
“If either Harry Kane and Sergio Aguero slip up, he or Mo Salah both have an opportunity.
“For me as a centre-forward, I believe that winning the Golden Boot is a very prestigious honour.
“It’s a fantastic achievement for any player to be top scorer in their division but to do it in the Premier League is extra special.”
Aldridge went on to note that Mane had stepped up at the ideal time for Liverpool – during team-mate Mohamed Salah’s longest goal-scoring drought for the club.
“Sadio has now got himself into a situation in which he’s got an outside chance of getting it – although I don’t think it’s got anything to do with me telling him,” he added.
“Mane’s hot streak has come at an ideal time though with Salah suffering a dry spell.”
Liverpool are looking to win their first English league title in 29 years, and with just seven games remaining, they sit two points clear at the top of the league.
Title rivals Manchester City, though, have a game in hand on Jurgen Klopp’s men and could leapfrog them with a win.
City are still in contention to win a historic quadruple while Liverpool are continuing to handle their business in the Europe, where they come up against Porto in the Champions League quarter-finals.